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VPREB1 Antibody

CAT: 0223-60-450Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-450Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene belongs to the immunoglobulin superfamily and is expressed selectively at the early stages of B cell development, namely, in proB and early preB cells. This gene encodes the iota polypeptide chain that is associated with the Ig-mu chain to form a molecular complex which is expressed on the surface of pre-B cells. The complex is thought to regulate Ig gene rearrangements in the early steps of B-cell differentiation.
NCBI Gene ID
7441
Swiss Prot
P12018
Accession Number
P12018
Host
Rabbit
Reactivity
Human
Immunogen
This VPREB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 71-99 amino acids from the Central region of human VPREB1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
17 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
VPREB1
NCBI Official Name
Immunoglobulin iota chain
NCBI Organism
Homo sapiens
Background Reference 01
Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)
Background Reference 02
Wu, C., et al. Proteomics 7 (11) :1775-1785 (2007)
Background Reference 03
Rossi, B., et al. J. Immunol. 177 (2) :796-803 (2006)
Background Reference 04
Collins, J.E., et al. Genome Biol. (10), R84 (2004) :
Other Product Names
Immunoglobulin iota chain, CD179 antigen-like family member A, Protein VPreB1, V (pre) B protein, VpreB protein, CD179a, VPREB1, VPREB
Tested Applications
WB
Protein ID
9911096
Physical Properties
Liquid

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