VPREB1 Antibody

• Background:

  The protein encoded by this gene belongs to the immunoglobulin superfamily and is expressed selectively at the early stages of B cell development, namely, in proB and early preB cells. This gene encodes the iota polypeptide chain that is associated with the Ig-mu chain to form a molecular complex which is expressed on the surface of pre-B cells. The complex is thought to regulate Ig gene rearrangements in the early steps of B-cell differentiation.

• NCBI Gene ID:

  7441

• Swiss Prot:

  P12018

• Accession Number:

  P12018

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This VPREB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 71-99 amino acids from the Central region of human VPREB1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  17 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  VPREB1

• NCBI Official Name:

  Immunoglobulin iota chain

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)

• Background Reference 02:

  Wu, C., et al. Proteomics 7 (11) :1775-1785 (2007)

• Background Reference 03:

  Rossi, B., et al. J. Immunol. 177 (2) :796-803 (2006)

• Background Reference 04:

  Collins, J.E., et al. Genome Biol. (10), R84 (2004) :

• Other Product Names:

  Immunoglobulin iota chain, CD179 antigen-like family member A, Protein VPreB1, V (pre) B protein, VpreB protein, CD179a, VPREB1, VPREB

• Tested Applications:

  WB

• Protein ID:

  9911096

• Physical Properties:

  Liquid