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Mouse Nod1 Antibody

CAT: 0223-60-392Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-392Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Enhances caspase-9-mediated apoptosis. Induces NF-kappa-B activity via RIPK2 and IKK-gamma. Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS) . Forms an intracellular sensing system along with ARHGEF2 for the detection of microbial effectors during cell invasion by pathogens (By similarity) .
NCBI Gene ID
107607
Swiss Prot
Q8BHB0
Accession Number
Q8BHB0
Host
Rabbit
Reactivity
Mouse
Immunogen
This Mouse Nod1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 556-584 amino acids from the Central region of mouse Nod1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Inflammasomes
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
108 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
Nod1
NCBI Official Name
Nucleotide-binding oligomerization domain-containing protein 1
NCBI Organism
Mus musculus
Background Reference 01
Moreno, L., et al. Br. J. Pharmacol. 160 (8) :1997-2007 (2010)
Background Reference 02
Iyer, J.K., et al. Infect. Immun. 78 (6) :2418-2428 (2010)
Background Reference 03
Watanabe, T., et al. J. Clin. Invest. 120 (5) :1645-1662 (2010)
Background Reference 04
Toma, C., et al. J. Immunol. 184 (9) :5287-5297 (2010)
Other Product Names
Nucleotide-binding oligomerization domain-containing protein 1, Caspase recruitment domain-containing protein 4, Nod1, Card4
Tested Applications
WB
Physical Properties
Liquid

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