NOD1 Antibody

CAT: 0223-5947-01Size: 0.02 mgDry Ice: NoHazardous: No
CAT#:0223-5947-01Size:0.02 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
NOD1 Antibody: NOD1 is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD1 contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and ten tandem leucine-rich repeats (LRRs) in its C-terminus. The CARD is involved in apoptotic signaling, and NOD1 activates caspase-9 and NF-κ B. LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid.
NCBI Gene ID
10392
Swiss Prot
Q9Y239
Accession Number
Q9Y239
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Innate Immunity, Inflammasomes
Purification
NOD1 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1287 - EL4 Cell Lysate
Concentration
1 mg/mL
Buffer
NOD1 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
NOD1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Symbol
NOD1
NCBI Official Name
Nucleotide-binding oligomerization domain containing 1
NCBI Organism
Homo sapiens
Background Reference 01
Kufer TA, Banks DJ, and Philpott DJ. Innate immune sensing of microbes by Nod proteins. Ann. NY Acad. Sci.2006; 1072:19-27.
Background Reference 02
Inohara N, Koseki T, del Peso L, et al. Nod1, an Apaf-1-like activator of caspase-9 and nuclear factor-kappaB. J. Biol. Chem.1999; 274:14560-7.
Background Reference 03
Chamaillard M, Hashimoto M, Horie Y, et al. An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid. Nat. Immunol.2003; 4:702-7.
Other Product Names
NOD1 Antibody: CARD4, NLRC1, CLR7.1, Caspase recruitment domain-containing protein 4, Nucleotide-binding oligomerization domain-containing protein 1
Tested Applications
ELISA, WB
Protein ID
20137579
Physical Properties
Liquid

Related Products

CatalogName
5947PNOD1 Peptide
42-460PNOD1 Peptide
2511-002mgNOD2 Antibody
5955-002mgNOD6 Antibody
5955-01mgNOD6 Antibody
2513-01NOD2 Antibody
5949-01NOD3 Antibody
5955-01NOD6 Antibody
5953-01mgNOD5 Antibody
5951-002mgNOD4 Antibody

Alternative Products

CatalogName
MBS855930-01NOD1 Antibody

Popular Products