SNAPC1 Antibody

• Background:

  Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.

• NCBI Gene ID:

  6617

• Swiss Prot:

  Q16533

• Accession Number:

  Q16533

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This SNAPC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 139-168 amino acids from the Central region of human SNAPC1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Monkey

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  43 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  SNAPC1

• NCBI Official Name:

  SnRNA-activating protein complex subunit 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Gu, L., et al. J. Biol. Chem. 280 (30) :27697-27704 (2005)

• Background Reference 02:

  Hinkley, C.S., et al. J. Biol. Chem. 278 (20) :18649-18657 (2003)

• Background Reference 03:

  Ma, B., et al. J. Biol. Chem. 276 (7) :5027-5035 (2001)

• Background Reference 04:

  Hirsch, H.A., et al. Mol. Cell. Biol. 20 (24) :9182-9191 (2000)

• Other Product Names:

  SnRNA-activating protein complex subunit 1, SNAPc subunit 1, Proximal sequence element-binding transcription factor subunit gamma, PSE-binding factor subunit gamma, PTF subunit gamma, Small nuclear RNA-activating complex polypeptide 1, snRNA-activating protein complex 43 kDa subunit, SNAPc 43 kDa subunit, SNAPC1, SNAP43

• Tested Applications:

  WB

• Protein ID:

  8134716

• Physical Properties:

  Liquid