GRPEL2 Antibody

• Background :

  Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. Stimulates ATPase activity of mt-HSP70. May also serve to modulate the interconversion of oligomeric (inactive) and monomeric (active) forms of mt-HSP70 (By similarity) .

• NCBI Gene ID :

  134266

• Swiss Prot :

  Q8TAA5

• Accession Number :

  Q8TAA5

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  This GRPEL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-43 amino acids from the N-terminal region of human GRPEL2.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  25 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  GRPEL2

• NCBI Official Name :

  GrpE protein homolog 2, mitochondrial

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)

• Background Reference 02 :

  Naylor, D.J., et al. J. Biol. Chem. 273 (33) :21169-21177 (1998)

• Other Product Names :

  GrpE protein homolog 2, mitochondrial, Mt-GrpE#2, GRPEL2

• Tested Applications :

  WB

• Physical Properties :

  Liquid