GRPEL2 Antibody

• Background:

  Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. Stimulates ATPase activity of mt-HSP70. May also serve to modulate the interconversion of oligomeric (inactive) and monomeric (active) forms of mt-HSP70 (By similarity) .

• NCBI Gene ID:

  134266

• Swiss Prot:

  Q8TAA5

• Accession Number:

  Q8TAA5

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This GRPEL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-43 amino acids from the N-terminal region of human GRPEL2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  25 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  GRPEL2

• NCBI Official Name:

  GrpE protein homolog 2, mitochondrial

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)

• Background Reference 02:

  Naylor, D.J., et al. J. Biol. Chem. 273 (33) :21169-21177 (1998)

• Other Product Names:

  GrpE protein homolog 2, mitochondrial, Mt-GrpE#2, GRPEL2

• Tested Applications:

  WB

• Physical Properties:

  Liquid