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UBASH3A Antibody

CAT: 0223-60-363Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-363Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
UBASH3A interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors, EGFR and PDGFRB, on the cell surface.
NCBI Gene ID
53347
Swiss Prot
P57075
Accession Number
P57075
Host
Rabbit
Reactivity
Mouse
Immunogen
This UBASH3A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 313-340 amino acids from the Central region of human UBASH3A.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
74 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
UBASH3A
NCBI Official Name
Ubiquitin-associated and SH3 domain-containing protein A
NCBI Organism
Homo sapiens
Background Reference 01
Hinks, A., et al. Ann. Rheum. Dis. (2010) In press :
Background Reference 02
Stahl, E.A., et al. Nat. Genet. 42 (6) :508-514 (2010)
Background Reference 03
Jin, Y., et al. N. Engl. J. Med. 362 (18) :1686-1697 (2010)
Background Reference 04
Barrett, J.C., et al. Nat. Genet. 41 (6) :703-707 (2009)
Other Product Names
Ubiquitin-associated and SH3 domain-containing protein A, Cbl-interacting protein 4, CLIP4, Suppressor of T-cell receptor signaling 2, STS-2, T-cell ubiquitin ligand 1, TULA-1, UBASH3A, STS2
Tested Applications
WB
Protein ID
10720330
Physical Properties
Liquid

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