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XK Antibody

CAT: 0223-60-361Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-361Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This locus controls the synthesis of the Kell blood group 'precursor substance' (Kx) . Mutations in this gene have been associated with McLeod syndrome, an X-linked, recessive disorder characterized by abnormalities in the neuromuscular and hematopoietic systems. The encoded protein has structural characteristics of prokaryotic and eukaryotic membrane transport proteins.
NCBI Gene ID
7504
Swiss Prot
P51811
Accession Number
P51811
Host
Rabbit
Reactivity
Human
Immunogen
This XK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 83-111 amino acids from the N-terminal region of human XK.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
51 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
XK
NCBI Official Name
Membrane transport protein XK
NCBI Organism
Homo sapiens
Background Reference 01
Miranda, M., et al. Mov. Disord. 22 (9) :1358-1361 (2007)
Background Reference 02
Claperon, A., et al. Brain Res. 1147, 12-24 (2007) :
Background Reference 03
Walker, R.H., et al. Transfusion 47 (2) :299-305 (2007)
Background Reference 04
Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)
Other Product Names
Membrane transport protein XK, Kell complex 37 kDa component, Kx antigen, XK-related protein 1, XK, XKR1, XRG1
Tested Applications
WB
Protein ID
85700269
Physical Properties
Liquid

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