XK Antibody

• Background:

  This locus controls the synthesis of the Kell blood group 'precursor substance' (Kx) . Mutations in this gene have been associated with McLeod syndrome, an X-linked, recessive disorder characterized by abnormalities in the neuromuscular and hematopoietic systems. The encoded protein has structural characteristics of prokaryotic and eukaryotic membrane transport proteins.

• NCBI Gene ID:

  7504

• Swiss Prot:

  P51811

• Accession Number:

  P51811

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This XK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 83-111 amino acids from the N-terminal region of human XK.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  51 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  XK

• NCBI Official Name:

  Membrane transport protein XK

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Miranda, M., et al. Mov. Disord. 22 (9) :1358-1361 (2007)

• Background Reference 02:

  Claperon, A., et al. Brain Res. 1147, 12-24 (2007) :

• Background Reference 03:

  Walker, R.H., et al. Transfusion 47 (2) :299-305 (2007)

• Background Reference 04:

  Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)

• Other Product Names:

  Membrane transport protein XK, Kell complex 37 kDa component, Kx antigen, XK-related protein 1, XK, XKR1, XRG1

• Tested Applications:

  WB

• Protein ID:

  85700269

• Physical Properties:

  Liquid