MRPL46 Antibody

CAT: 0223-60-347Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-60-347Size:400 µL
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Background
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. [provided by RefSeq].
NCBI Gene ID
26589
Swiss Prot
Q9H2W6
Accession Number
Q9H2W6
Host
Rabbit
Reactivity
Human
Immunogen
This MRPL46 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 248-274 amino acids from the C-terminal region of human MRPL46.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
32 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
MRPL46
NCBI Official Name
39S ribosomal protein L46, mitochondrial
NCBI Organism
Homo sapiens
Background Reference 01
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 02
Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)
Background Reference 03
Zhang, Z., et al. Genomics 81 (5) :468-480 (2003)
Background Reference 04
Koc, E.C., et al. J. Biol. Chem. 276 (47) :43958-43969 (2001)
Other Product Names
39S ribosomal protein L46, mitochondrial, L46mt, MRP-L46, P2ECSL, MRPL46, C15orf4, LIECG2
Tested Applications
WB
Protein ID
52783325
Physical Properties
Liquid

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