SRP14 Antibody

• Background :

  Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.

• NCBI Gene ID :

  6727

• Swiss Prot :

  P37108

• Accession Number :

  P37108

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This SRP14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-55 amino acids from the Central region of human SRP14.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Homology :

  Predicted species reactivity based on immunogen sequence: Monkey

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  15 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:2000

• Symbol :

  SRP14

• NCBI Official Name :

  Signal recognition particle 14 kDa protein

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Mary, C., et al. RNA 16 (5) :969-979 (2010)

• Background Reference 02 :

  Lakkaraju, A.K., et al. Cell 133 (3) :440-451 (2008)

• Background Reference 03 :

  Yoshida, M., et al. Mol. Pharmacol. 73 (3) :987-994 (2008)

• Background Reference 04 :

  Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)

• Other Product Names :

  Signal recognition particle 14 kDa protein, SRP14, 18 kDa Alu RNA-binding protein, SRP14

• Tested Applications :

  WB

• Protein ID :

  116242801

• Physical Properties :

  Liquid