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SRP14 Antibody

CAT: 0223-60-309Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-309Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
NCBI Gene ID
6727
Swiss Prot
P37108
Accession Number
P37108
Host
Rabbit
Reactivity
Human
Immunogen
This SRP14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-55 amino acids from the Central region of human SRP14.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Monkey
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
15 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:2000
Symbol
SRP14
NCBI Official Name
Signal recognition particle 14 kDa protein
NCBI Organism
Homo sapiens
Background Reference 01
Mary, C., et al. RNA 16 (5) :969-979 (2010)
Background Reference 02
Lakkaraju, A.K., et al. Cell 133 (3) :440-451 (2008)
Background Reference 03
Yoshida, M., et al. Mol. Pharmacol. 73 (3) :987-994 (2008)
Background Reference 04
Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)
Other Product Names
Signal recognition particle 14 kDa protein, SRP14, 18 kDa Alu RNA-binding protein, SRP14
Tested Applications
WB
Protein ID
116242801
Physical Properties
Liquid

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