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SPANXE Antibody

CAT: 0223-60-307Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-60-307Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family of cancer/testis-associated genes, which are located in a cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene encodes a sperm protein that contains a consensus nuclear localization signal but, although a role in spermatogenesis is suggested, the specific function of this family member has not yet been determined.
NCBI Gene ID
64663
Swiss Prot
Q8TAD1
Accession Number
Q8TAD1
Host
Rabbit
Reactivity
Human
Immunogen
This SPANXE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-65 amino acids from the Central region of human SPANXE.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
11 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
SPANXE
NCBI Official Name
Sperm protein associated with the nucleus on the X chromosome E
NCBI Organism
Homo sapiens
Background Reference 01
Hansen, S., et al. Syst Biol Reprod Med 55, 18-26 (2010) :
Background Reference 02
Kouprina, N., et al. Genome Res. 15 (11) :1477-1486 (2005)
Background Reference 03
Zendman, A.J., et al. Gene 309 (2) :125-133 (2003)
Background Reference 04
Westbrook, V.A., et al. Biol. Reprod. 64 (1) :345-358 (2001)
Other Product Names
Sperm protein associated with the nucleus on the X chromosome E, Nuclear-associated protein SPAN-Xe, SPANX-E, SPANX family member E, SPANXE
Tested Applications
WB
Protein ID
85543354
Physical Properties
Liquid

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