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SSTR5 Antibody

CAT: 0223-60-259Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-259Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Somatostatin and its related peptide cortistatin exert multiple biological actions on normal and tumoral tissue targets by interacting with somatostatin receptors (SSTRs) . The protein encoded by this gene is one of the SSTRs, which is a multi-pass membrane protein and belongs to the G-protein coupled receptor 1 family. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase, and different regions of this receptor molecule are required for the activation of different signaling pathways. A mutation in this gene results in somatostatin analog resistance. Alternatively spliced transcript variants have been identified in this gene.
NCBI Gene ID
6755
Swiss Prot
P35346
Accession Number
P35346
Host
Rabbit
Reactivity
Human
Immunogen
This SSTR5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 311-339 amino acids from the C-terminal region of human SSTR5.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction, Growth Factors
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
39 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
SSTR5
NCBI Official Name
Somatostatin receptor type 5
NCBI Organism
Homo sapiens
Background Reference 01
Canzian, F., et al. Hum. Mol. Genet. 19 (19) :3873-3884 (2010)
Background Reference 02
Saus, E., et al.Psychiatr Res 44 (14) :971-978 (2010)
Background Reference 03
Pinheiro, A.P., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :
Background Reference 04
Duran-Prado, M., et al. J. Clin. Endocrinol. Metab. 95 (5) :2497-2502 (2010)
Other Product Names
Somatostatin receptor type 5, SS-5-R, SS5-R, SS5R, SSTR5
Tested Applications
WB
Protein ID
12644225
Physical Properties
Liquid

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