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CATSPER2 Antibody

CAT: 0223-60-254Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-254Size:400 µL
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Background
Calcium ions play a primary role in the regulation of sperm motility. This gene belongs to a family of putative cation channels that are specific to spermatozoa and localize to the flagellum. The protein family features a single repeat with six membrane-spanning segments and a predicted calcium-selective pore region. This gene is part of a tandem repeat on chromosome 15q15; the second copy of this gene is thought to be a pseudogene. Additional splice variants have been described but their full-length nature has not been determined.
NCBI Gene ID
117155
Swiss Prot
Q96P56
Accession Number
Q96P56
Host
Rabbit
Reactivity
Human
Immunogen
This CATSPER2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 472-500 amino acids from the C-terminal region of human CATSPER2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
62 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
CATSPER2
NCBI Official Name
Cation channel sperm-associated protein 2
NCBI Organism
Homo sapiens
Background Reference 01
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 02
Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)
Background Reference 03
Zhang, D., et al. J. Biol. Chem. 281 (31) :22332-22341 (2006)
Background Reference 04
Clapham, D.E., et al. Pharmacol. Rev. 57 (4) :451-454 (2005)
Other Product Names
Cation channel sperm-associated protein 2, CatSper2, CATSPER2
Tested Applications
WB
Protein ID
156631018
Physical Properties
Liquid

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