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PTCRA Antibody

CAT: 0223-60-241Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-241Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
In immature T cells the T-cell receptor beta-chain gene (TCRB; MIM 186930) is rearranged and expressed before the TCRA (MIM 186880) chain. At this early stage, TCRB can associate with the pre-T-cell receptor alpha chain (PTCRA) . The PTCRA, together with TCRB and the CD3 complex (see MIM 186740), minimally make up the pre-T cell receptor (pre-TCR), which regulates early T cell development.
NCBI Gene ID
171558
Swiss Prot
Q6ISU1
Accession Number
Q6ISU1
Host
Rabbit
Reactivity
Human
Immunogen
This PTCRA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 197-225 amino acids from the C-terminal region of human PTCRA.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
29 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PTCRA
NCBI Official Name
Pre T-cell antigen receptor alpha
NCBI Organism
Homo sapiens
Background Reference 01
Velez, D.R., et al. Am. J. Obstet. Gynecol. 200 (2), 209 (2009) :
Background Reference 02
Menon, R., et al. Reprod. Biol. Endocrinol. 7, 62 (2009) :
Background Reference 03
Velez, D.R., et al. PLoS ONE (9), E3283 (2008) :
Background Reference 04
Navarro, M.N., et al. Blood 110 (13) :4331-4340 (2007)
Other Product Names
Pre T-cell antigen receptor alpha, pT-alpha, pTa, pT-alpha-TCR, PTCRA
Tested Applications
WB
Protein ID
74736631
Physical Properties
Liquid

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