FERMT2 Antibody

• Background:

  FERMT2 participates in the connection between ECM adhesion sites and the actin cytoskeleton and also in the orchestration of actin assembly and cell shape modulation. Recruits migfilin (FBLP1) protein to cell-ECM focal adhesion sites.

• NCBI Gene ID:

  10979

• Swiss Prot:

  Q96AC1

• Accession Number:

  Q96AC1

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This FERMT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 641-669 amino acids from the C-terminal region of human FERMT2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Zebrafish, Mouse

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  78 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  FERMT2

• NCBI Official Name:

  Fermitin family homolog 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  An, Z., et al. Int. J. Cancer 127 (9) :1999-2008 (2010) Bledzka, K., et al. J. Biol. Chem. 285 (40) :30370-30374 (2010) Lai-Cheong, J.E., et al. Int. J. Biochem. Cell Biol. 42 (5) :595-603 (2010) Lai-Cheong, J.E., et al. J. Invest. Dermatol. 128 (9) :2156-2165 (2008) Ma, Y.Q., et al. J. Cell Biol. 181 (3) :439-446 (2008)

• Other Product Names:

  Fermitin family homolog 2, Kindlin-2, Mitogen-inducible gene 2 protein, MIG-2, Pleckstrin homology domain-containing family C member 1, PH domain-containing family C member 1, FERMT2, KIND2, MIG2, PLEKHC1

• Tested Applications:

  WB

• Protein ID:

  38258220

• Physical Properties:

  Liquid