HAS3 Antibody

• Background:

  The protein encoded by this gene is involved in the synthesis of the unbranched glycosaminoglycan hyaluronan, or hyaluronic acid, which is a major constituent of the extracellular matrix. This gene is a member of the NODC/HAS gene family. Compared to the proteins encoded by other members of this gene family, this protein appears to be more of a regulator of hyaluronan synthesis. Alternative splicing results in multiple transcript variants.

• NCBI Gene ID:

  3038

• Swiss Prot:

  O00219

• Accession Number:

  O00219

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This HAS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 137-164 amino acids from the Central region of human HAS3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  63 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  HAS3

• NCBI Official Name:

  Hyaluronan synthase 3

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Dunn, K.M., et al. Surgery 145 (3) :322-329 (2009)

• Background Reference 02:

  Nykopp, T.K., et al. BMC Cancer 9, 143 (2009) :

• Background Reference 03:

  Nair, S., et al. J. Nephrol. 21 (3) :400-405 (2008)

• Background Reference 04:

  Campo, G.M., et al. Mol. Cell. Biochem. 292 (1-2), 169-178 (2006) :

• Other Product Names:

  Hyaluronan synthase 3, Hyaluronate synthase 3, Hyaluronic acid synthase 3, HA synthase 3, HAS3

• Tested Applications:

  WB

• Physical Properties:

  Liquid