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TREML1 Antibody

CAT: 0223-60-060Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-060Size:400 µL
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Background
TREML1 is located in a gene cluster on chromosome 6 with the single Ig variable (IgV) domain activating receptors TREM1 (MIM 605085) and TREM2 (MIM 605086), but it has distinct structural and functional properties. TREML1 enhances calcium signaling in an SHP2 (PTPN11; MIM 176876) -dependent manner (Allcock et al., 2003 [PubMed 12645956]; Barrow et al., 2004 [PubMed 15128762]) .[supplied by OMIM].
NCBI Gene ID
340205
Swiss Prot
Q86YW5
Accession Number
Q86YW5
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This TREML1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 215-241 amino acids from the C-terminal region of human TREML1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
33 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
TREML1
NCBI Official Name
Trem-like transcript 1 protein
NCBI Organism
Homo sapiens
Background Reference 01
Morales, J., et al. Blood Coagul. Fibrinolysis 21 (3) :229-236 (2010)
Background Reference 02
Washington, A.V., et al. J. Clin. Invest. 119 (6) :1489-1501 (2009)
Background Reference 03
Ford, J.W., et al. Curr. Opin. Immunol. 21 (1) :38-46 (2009)
Background Reference 04
Nurden, A.T., et al. Thromb. Haemost. 100 (1) :45-51 (2008)
Other Product Names
Trem-like transcript 1 protein, TLT-1, Triggering receptor expressed on myeloid cells-like protein 1, TREML1, TLT1
Tested Applications
WB
Protein ID
116256098
Physical Properties
Liquid

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