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GTF3A Antibody

CAT: 0223-60-057Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-057Size:400 µL
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Background
The product of this gene is a zinc finger protein with nine Cis[2]-His[2] zinc finger domains. It functions as an RNA polymerase III transcription factor to induce transcription of the 5S rRNA genes. The protein binds to a 50 bp internal promoter in the 5S genes called the internal control region (ICR), and nucleates formation of a stable preinitiation complex. This complex recruits the TFIIIC and TFIIIB transcription factors and RNA polymerase III to form the complete transcription complex. The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis, protein homology, and the size of the purified protein. [provided by RefSeq].
NCBI Gene ID
2971
Swiss Prot
Q92664
Accession Number
Q92664
Host
Rabbit
Reactivity
Human
Immunogen
This GTF3A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 308-334 amino acids from the C-terminal region of human GTF3A.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
42 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
GTF3A
NCBI Official Name
Transcription factor IIIA
NCBI Organism
Homo sapiens
Background Reference 01
Wu, C., et al. Proteomics 7 (11) :1775-1785 (2007)
Background Reference 02
Newton-Cheh, C., et al. BMC Med. Genet.SUPPL 1, S7 (2007) :
Background Reference 03
Weser, S., et al. Nucleic Acids Res. 31 (9) :2408-2416 (2003)
Background Reference 04
Hanas, J.S., et al. Gene 282 (1-2), 43-52 (2002) :
Other Product Names
Transcription factor IIIA, TFIIIA, GTF3A
Tested Applications
WB
Protein ID
172045838
Physical Properties
Liquid

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