GTF3A Antibody

• Background:

  The product of this gene is a zinc finger protein with nine Cis[2]-His[2] zinc finger domains. It functions as an RNA polymerase III transcription factor to induce transcription of the 5S rRNA genes. The protein binds to a 50 bp internal promoter in the 5S genes called the internal control region (ICR), and nucleates formation of a stable preinitiation complex. This complex recruits the TFIIIC and TFIIIB transcription factors and RNA polymerase III to form the complete transcription complex. The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis, protein homology, and the size of the purified protein. [provided by RefSeq].

• NCBI Gene ID:

  2971

• Swiss Prot:

  Q92664

• Accession Number:

  Q92664

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This GTF3A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 308-334 amino acids from the C-terminal region of human GTF3A.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  42 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  GTF3A

• NCBI Official Name:

  Transcription factor IIIA

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Wu, C., et al. Proteomics 7 (11) :1775-1785 (2007)

• Background Reference 02:

  Newton-Cheh, C., et al. BMC Med. Genet.SUPPL 1, S7 (2007) :

• Background Reference 03:

  Weser, S., et al. Nucleic Acids Res. 31 (9) :2408-2416 (2003)

• Background Reference 04:

  Hanas, J.S., et al. Gene 282 (1-2), 43-52 (2002) :

• Other Product Names:

  Transcription factor IIIA, TFIIIA, GTF3A

• Tested Applications:

  WB

• Protein ID:

  172045838

• Physical Properties:

  Liquid