SEC23B Antibody

• Background:

  The protein encoded by this gene is a member of the SEC23 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec23p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The function of this gene product has been implicated in cargo selection and concentration. Multiple alternatively spliced transcript variants have been identified in this gene.

• NCBI Gene ID:

  10483

• Swiss Prot:

  Q15437

• Accession Number:

  Q15437

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This SEC23B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 655-684 amino acids from the C-terminal region of human SEC23B.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine, Mouse

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  86 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  SEC23B

• NCBI Official Name:

  Protein transport protein Sec23B

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

• Background Reference 02:

  Fermo, E., et al. Blood Cells Mol. Dis. 45 (1) :20-22 (2010)

• Background Reference 03:

  Bianchi, P., et al. Hum. Mutat. 30 (9) :1292-1298 (2009)

• Background Reference 04:

  Schwarz, K., et al. Nat. Genet. 41 (8) :936-940 (2009)

• Other Product Names:

  Protein transport protein Sec23B, SEC23-related protein B, SEC23B

• Tested Applications:

  WB

• Protein ID:

  20141794

• Physical Properties:

  Liquid