MRPS10 Antibody

• Background :

  Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S10P family. Pseudogenes corresponding to this gene are found on chromosomes 1q, 3p, and 9p. [provided by RefSeq].

• NCBI Gene ID :

  55173

• Swiss Prot :

  P82664

• Accession Number :

  P82664

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This MRPS10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 113-141 amino acids from the Central region of human MRPS10.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Homology :

  Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  23 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  MRPS10

• NCBI Official Name :

  28S ribosomal protein S10, mitochondrial

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)

• Background Reference 02 :

  Mungall, A.J., et al. Nature 425 (6960) :805-811 (2003)

• Background Reference 03 :

  Zhang, Z., et al. Genomics 81 (5) :468-480 (2003)

• Background Reference 04 :

  Jia, L., et al. Genomics 79 (1) :7-17 (2002)

• Other Product Names :

  28S ribosomal protein S10, mitochondrial, MRP-S10, S10mt, MRPS10

• Tested Applications :

  WB

• Physical Properties :

  Liquid