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MRPS11 Antibody

CAT: 0223-59-285Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-59-285Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that contains a high level of sequence similarity with ribosomal protein S11P family members. A pseudogene corresponding to this gene is found on chromosome 20. Sequence analysis identified two transcript variants that encode different protein isoforms.
NCBI Gene ID
64963
Swiss Prot
P82912
Accession Number
P82912
Host
Rabbit
Reactivity
Human
Immunogen
This MRPS11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 42-69 amino acids from the Central region of human MRPS11.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
21 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
MRPS11
NCBI Official Name
28S ribosomal protein S11, mitochondrial
NCBI Organism
Homo sapiens
Background Reference 01
Ishiguchi, H., et al. Int. J. Cancer 111 (6) :900-909 (2004)
Background Reference 02
Zhang, Z., et al. Genomics 81 (5) :468-480 (2003)
Background Reference 03
Kenmochi, N., et al. Genomics 77 (1-2), 65-70 (2001) :
Background Reference 04
Suzuki, T., et al. J. Biol. Chem. 276 (35) :33181-33195 (2001)
Other Product Names
28S ribosomal protein S11, mitochondrial, MRP-S11, S11mt, Cervical cancer proto-oncogene 2 protein, HCC-2, MRPS11, RPMS11
Tested Applications
WB
Protein ID
21263985
Physical Properties
Liquid

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