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LAX1 Antibody

CAT: 0223-60-025Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-025Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
LAX1 negatively regulates TCR (T-cell antigen receptor) -mediated signaling in T-cells and BCR (B-cell antigen receptor) -mediated signaling in B-cells.
NCBI Gene ID
54900
Swiss Prot
Q8IWV1
Accession Number
Q8IWV1
Host
Rabbit
Reactivity
Human
Immunogen
This LAX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 369-398 amino acids from the C-terminal region of human LAX1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
44 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
LAX1
NCBI Official Name
Lymphocyte transmembrane adapter 1
NCBI Organism
Homo sapiens
Background Reference 01
Ehret, G.B., et al. Eur. J. Hum. Genet. 17 (12) :1650-1657 (2009)
Background Reference 02
Shapiro, M.J., et al. J. Immunol. 181 (10) :7055-7061 (2008)
Background Reference 03
Zhu, M., et al. J. Immunol. 174 (9) :5612-5619 (2005)
Background Reference 04
Zhu, M., et al. J. Biol. Chem. 277 (48) :46151-46158 (2002)
Other Product Names
Lymphocyte transmembrane adapter 1, Linker for activation of X cells, Membrane-associated adapter protein LAX, LAX1, LAX
Tested Applications
WB
Protein ID
74728197
Physical Properties
Liquid

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