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PGLYRP1 Antibody

CAT: 0223-60-003Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-003Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
PGLYRP1 is a pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria, and has bacteriostatic activity towards Gram-negative bacteria. Plays a role in innate immunity.
NCBI Gene ID
8993
Swiss Prot
O75594
Accession Number
O75594
Host
Rabbit
Reactivity
Human
Immunogen
This PGLYRP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-174 amino acids from the C-terminal region of human PGLYRP1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Immunology, Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
22 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PGLYRP1
NCBI Official Name
Peptidoglycan recognition protein 1
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 02
Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)
Background Reference 03
Dukhanina, E.A., et al. Proc. Natl. Acad. Sci. U.S.A. 106 (33) :13963-13967 (2009)
Background Reference 04
Rohatgi, A., et al. Atherosclerosis 203 (2) :569-575 (2009)
Other Product Names
Peptidoglycan recognition protein 1, Peptidoglycan recognition protein short, PGRP-S, PGLYRP1, PGLYRP, PGRP, TNFSF3L
Tested Applications
WB
Physical Properties
Liquid

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