LDOC1L Antibody

CAT: 0223-59-990Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-59-990Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
LDOC1 (Leucine zipper protein downregulated in cancer cells) is a 146 amino acid nuclear protein that contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is downregulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kB (NF-kB) . The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers. LDOC1L (Leucine zipper protein down-regulated in cancer cells-like), also known as MART6 (Mammalian retrotransposon-derived protein 6), is a 239 amino acid protein that belongs to the LDOC1 family.
NCBI Gene ID
84247
Swiss Prot
Q6ICC9
Accession Number
Q6ICC9
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This LDOC1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 160-186 amino acids from the C-terminal region of human LDOC1L.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
26 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
LDOC1L
NCBI Official Name
Protein LDOC1L
NCBI Organism
Homo sapiens
Background Reference 01
Brandt, J., et al. Gene 345 (1) :101-111 (2005)
Background Reference 02
Brandt, J., et al. Cytogenet. Genome Res. 110 (1-4), 307-317 (2005) :
Background Reference 03
Collins, J.E., et al. Genome Biol. (10), R84 (2004) :
Other Product Names
Protein LDOC1L, Leucine zipper protein down-regulated in cancer cells-like, Mammalian retrotransposon-derived protein 6, LDOC1L, MAR6, MART6
Tested Applications
WB
Protein ID
74762303
Physical Properties
Liquid

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