CHMP5 Antibody

CAT: 0223-59-959Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-59-959Size:400 µL
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs) . Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]) .
NCBI Gene ID
51510
Swiss Prot
Q9NZZ3
Accession Number
Q9NZZ3
Host
Rabbit
Reactivity
Human
Immunogen
This CHMP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 178-204 amino acids from the C-terminal region of human CHMP5.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
25 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
CHMP5
NCBI Official Name
Charged multivesicular body protein 5
NCBI Organism
Homo sapiens
Background Reference 01
Wang, H.R., et al. Zhongguo Shi Yan Xue Ye Xue Za Zhi 16 (2) :282-285 (2008)
Background Reference 02
Row, P.E., et al. J. Biol. Chem. 282 (42) :30929-30937 (2007)
Background Reference 03
Huang, H.H., et al. Zhongguo Shi Yan Xue Ye Xue Za Zhi 15 (4) :738-742 (2007)
Background Reference 04
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Other Product Names
Charged multivesicular body protein 5, Chromatin-modifying protein 5, SNF7 domain-containing protein 2, Vacuolar protein sorting-associated protein 60, Vps60, hVps60, CHMP5, C9orf83, SNF7DC2
Tested Applications
WB
Protein ID
51702157
Physical Properties
Liquid

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