FRMD3 Antibody

• Background:

  Protein 4.1 of red blood cells, or 4.1R (EPB41; MIM 130500), is a multifunctional protein essential for maintaining erythrocyte shape and membrane mechanical properties. The protein 4.1 family comprises a group of structural proteins that includes, in addition to 4.1R, 4.1G (general type; MIM 603237), 4.1B (brain type; MIM 605331), 4.1N (neuron type; MIM 602879), and 4.1O (ovary type) .

• NCBI Gene ID:

  257019

• Swiss Prot:

  A2A2Y4

• Accession Number:

  A2A2Y4

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This FRMD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 250-279 amino acids from the Central region of human FRMD3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  69 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  FRMD3

• NCBI Official Name:

  FERM domain-containing protein 3

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Maeda, S., et al. Diabetes (2010) In press :

• Background Reference 02:

  Rose, J. Phd, et al. Mol. Med. (2010) In press :

• Background Reference 03:

  Pezzolesi, M.G., et al. Diabetes 58 (6) :1403-1410 (2009)

• Background Reference 04:

  Haase, D., et al. Oncogene 26 (30) :4464-4468 (2007)

• Other Product Names:

  FERM domain-containing protein 3, Band 41-like protein 4O, Ovary type protein 41, 41O, FRMD3, EPB41L4O

• Tested Applications:

  WB

• Physical Properties:

  Liquid