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PKNOX2 Antibody

CAT: 0223-59-874Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-59-874Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Homeodomain proteins are sequence-specific transcription factors that share a highly conserved DNA-binding domain and play fundamental roles in cell proliferation, differentiation, and death. PKNOX2 belongs to the TALE (3-amino acid loop extension) class of homeodomain proteins characterized by a 3-amino acid extension between alpha helices 1 and 2 within the homeodomain (Imoto et al., 2001 [PubMed 11549286]) .
NCBI Gene ID
63876
Swiss Prot
Q96KN3
Accession Number
Q96KN3
Host
Rabbit
Reactivity
Human
Immunogen
This PKNOX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 298-324 amino acids from the Central region of human PKNOX2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
52 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PKNOX2
NCBI Official Name
Homeobox protein PKNOX2
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 02
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 03
Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)
Background Reference 04
Chen, X., et al. Proc. Natl. Acad. Sci. U.S.A. (2009) In press :
Other Product Names
Homeobox protein PKNOX2, Homeobox protein PREP-2, PBX/knotted homeobox 2, PKNOX2, PREP2
Tested Applications
WB
Protein ID
115311621
Physical Properties
Liquid

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