SSX3 Antibody

• Background:

  The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t (X;18) translocation characteristically found in all synovial sarcomas. This gene appears not to be involved in this type of chromosome translocation. Two transcript variants encoding distinct isoforms have been identified for this gene.

• NCBI Gene ID:

  10214

• Swiss Prot:

  Q99909

• Accession Number:

  Q99909

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This SSX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 53-80 amino acids from the Central region of human SSX3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  22 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  SSX3

• NCBI Official Name:

  Protein SSX3

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Ross, M.T., et al. Nature 434 (7031) :325-337 (2005)

• Background Reference 02:

  Gure, A.O., et al. Int. J. Cancer 101 (5) :448-453 (2002)

• Background Reference 03:

  De Bruijn, D.R., et al. Genes Chromosomes Cancer 34 (3) :285-298 (2002)

• Background Reference 04:

  Gure, A.O., et al. Int. J. Cancer 72 (6) :965-971 (1997)

• Other Product Names:

  Protein SSX3, Cancer/testis antigen 53, CT53, SSX3

• Tested Applications:

  WB

• Protein ID:

  84028266

• Physical Properties:

  Liquid