SSX3 Antibody

CAT: 0223-59-853Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-59-853Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t (X;18) translocation characteristically found in all synovial sarcomas. This gene appears not to be involved in this type of chromosome translocation. Two transcript variants encoding distinct isoforms have been identified for this gene.
NCBI Gene ID
10214
Swiss Prot
Q99909
Accession Number
Q99909
Host
Rabbit
Reactivity
Human
Immunogen
This SSX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 53-80 amino acids from the Central region of human SSX3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
22 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
SSX3
NCBI Official Name
Protein SSX3
NCBI Organism
Homo sapiens
Background Reference 01
Ross, M.T., et al. Nature 434 (7031) :325-337 (2005)
Background Reference 02
Gure, A.O., et al. Int. J. Cancer 101 (5) :448-453 (2002)
Background Reference 03
De Bruijn, D.R., et al. Genes Chromosomes Cancer 34 (3) :285-298 (2002)
Background Reference 04
Gure, A.O., et al. Int. J. Cancer 72 (6) :965-971 (1997)
Other Product Names
Protein SSX3, Cancer/testis antigen 53, CT53, SSX3
Tested Applications
WB
Protein ID
84028266
Physical Properties
Liquid

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