ABCC9 Antibody

CAT: 0223-59-820Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-59-820Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White) . This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is thought to form ATP-sensitive potassium channels in cardiac, skeletal, and vascular and non-vascular smooth muscle. Protein structure suggests a role as the drug-binding channel-modulating subunit of the extrapancreatic ATP-sensitive potassium channels. No disease has been associated with this gene thus far. Alternative splicing of this gene results in several products, two of which result from differential usage of two terminal exons and one of which results from exon deletion.
NCBI Gene ID
10060
Swiss Prot
O60706
Accession Number
O60706
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This ABCC9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 640-669 amino acids from the Central region of human ABCC9.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
174 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
ABCC9
NCBI Official Name
ATP-binding cassette sub-family C member 9
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 02
Zimmerman, R.S., et al. Genet. Med. 12 (5) :268-278 (2010)
Background Reference 03
Ellis, J.A., et al. Physiol. Genomics 40 (3) :184-188 (2010)
Background Reference 04
Kim, S.J., et al. Biochem. Biophys. Res. Commun. 391 (1) :974-978 (2010)
Other Product Names
ATP-binding cassette sub-family C member 9, Sulfonylurea receptor 2, ABCC9, SUR2
Tested Applications
WB
Physical Properties
Liquid

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