ADNP Antibody

• Background:

  Vasoactive intestinal peptide is a neuroprotective factor that has a stimulatory effect on the growth of some tumor cells and an inhibitory effect on others. This gene encodes a protein that is upregulated by vasoactive intestinal peptide and may be involved in its stimulatory effect on certain tumor cells. The encoded protein contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor. This gene is also upregulated in normal proliferative tissues. Finally, the encoded protein may increase the viability of certain cell types through modulation of p53 activity. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq].

• NCBI Gene ID:

  23394

• Swiss Prot:

  Q9H2P0

• Accession Number:

  Q9H2P0

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This ADNP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 831-860 amino acids from the C-terminal region of human ADNP.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Neuroscience

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  124 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  ADNP

• NCBI Official Name:

  Activity-dependent neuroprotector homeobox protein

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Braitch, M., et al. Neuroimmunomodulation 17 (2) :120-125 (2010)

• Background Reference 02:

  Mandel, S., et al. J. Biol. Chem. 282 (47) :34448-34456 (2007)

• Background Reference 03:

  Wu, C., et al. Proteomics 7 (11) :1775-1785 (2007)

• Background Reference 04:

  Matsuoka, S., et al. Science 316 (5828) :1160-1166 (2007)

• Other Product Names:

  Activity-dependent neuroprotector homeobox protein, Activity-dependent neuroprotective protein, ADNP, ADNP1, KIAA0784

• Tested Applications:

  WB

• Protein ID:

  24636245

• Physical Properties:

  Liquid