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ADNP Antibody

CAT: 0223-59-817Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-59-817Size:400 µL
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Background
Vasoactive intestinal peptide is a neuroprotective factor that has a stimulatory effect on the growth of some tumor cells and an inhibitory effect on others. This gene encodes a protein that is upregulated by vasoactive intestinal peptide and may be involved in its stimulatory effect on certain tumor cells. The encoded protein contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor. This gene is also upregulated in normal proliferative tissues. Finally, the encoded protein may increase the viability of certain cell types through modulation of p53 activity. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq].
NCBI Gene ID
23394
Swiss Prot
Q9H2P0
Accession Number
Q9H2P0
Host
Rabbit
Reactivity
Human
Immunogen
This ADNP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 831-860 amino acids from the C-terminal region of human ADNP.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
124 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
ADNP
NCBI Official Name
Activity-dependent neuroprotector homeobox protein
NCBI Organism
Homo sapiens
Background Reference 01
Braitch, M., et al. Neuroimmunomodulation 17 (2) :120-125 (2010)
Background Reference 02
Mandel, S., et al. J. Biol. Chem. 282 (47) :34448-34456 (2007)
Background Reference 03
Wu, C., et al. Proteomics 7 (11) :1775-1785 (2007)
Background Reference 04
Matsuoka, S., et al. Science 316 (5828) :1160-1166 (2007)
Other Product Names
Activity-dependent neuroprotector homeobox protein, Activity-dependent neuroprotective protein, ADNP, ADNP1, KIAA0784
Tested Applications
WB
Protein ID
24636245
Physical Properties
Liquid

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