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OSTM1 Antibody

CAT: 0223-59-814Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-59-814Size:400 µL
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Background
This gene encodes a protein that may be involved in the degradation of G proteins via the ubiquitin-dependent proteasome pathway. The encoded protein binds to members of subfamily A of the regulator of the G-protein signaling (RGS) family through an N-terminal leucine-rich region. This protein also has a central RING finger-like domain and E3 ubiquitin ligase activity. This protein is highly conserved from flies to humans. Defects in this gene may cause the autosomal recessive, infantile malignant form of osteopetrosis.
NCBI Gene ID
28962
Swiss Prot
Q86WC4
Accession Number
Q86WC4
Host
Rabbit
Reactivity
Human
Immunogen
This OSTM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 292-321 amino acids from the C-terminal region of human OSTM1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Cell Cycle, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
37 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
OSTM1
NCBI Official Name
Osteopetrosis-associated transmembrane protein 1
NCBI Organism
Homo sapiens
Background Reference 01
Yerges, L.M., et al. J. Bone Miner. Res. 24 (12) :2039-2049 (2009)
Background Reference 02
Mazzolari, E., et al. Am. J. Hematol. 84 (8) :473-479 (2009)
Background Reference 03
Vieira, A.R., et al. Genet. Med. 10 (9) :668-674 (2008)
Background Reference 04
Feigin, M.E., et al. Cell. Signal. 20 (5) :949-957 (2008)
Other Product Names
Osteopetrosis-associated transmembrane protein 1, Chloride channel 7 beta subunit, OSTM1, GL
Tested Applications
WB
Protein ID
51316434
Physical Properties
Liquid

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