HAUS8 Antibody

• Background:

  HAUS8 is 1 of 8 subunits of the 390-kD human augmin complex, or HAUS complex. The augmin complex was first identified in Drosophila, and its name comes from the Latin verb 'augmentare, ' meaning 'to increase.' The augmin complex is a microtubule-binding complex involved in microtubule generation within the mitotic spindle and is vital to mitotic spindle assembly (Goshima et al., 2008 [PubMed 18443220]; Uehara et al., 2009 [PubMed 19369198]) .

• NCBI Gene ID:

  93323

• Swiss Prot:

  Q9BT25

• Accession Number:

  Q9BT25

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This HAUS8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-54 amino acids from the N-terminal region of human HAUS8.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  45 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  HAUS8

• NCBI Official Name:

  HAUS augmin-like complex subunit 8

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Wu, G., et al. Mol. Biol. Cell 20 (22) :4686-4695 (2009)

• Background Reference 02:

  Lawo, S., et al. Curr. Biol. 19 (10) :816-826 (2009)

• Background Reference 03:

  Uehara, R., et al. Proc. Natl. Acad. Sci. U.S.A. 106 (17) :6998-7003 (2009)

• Background Reference 04:

  Wu, G., et al. Mol. Cell. Biol. 28 (11) :3652-3662 (2008)

• Other Product Names:

  HAUS augmin-like complex subunit 8, HEC1/NDC80-interacting centrosome-associated protein 1, Sarcoma antigen NY-SAR-48, HAUS8, HICE1

• Tested Applications:

  WB

• Protein ID:

  229462967

• Physical Properties:

  Liquid