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DUS2L Antibody

CAT: 0223-59-760Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-59-760Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Dihydrouridine synthase catalyzes reduction of the 5,6-double bond of a uridine residue on the displacement loop of tRNA. The resultant modified base, 5,6-dihydrouridine, appears to increase the conformational flexibility and dynamic motion of tRNA (Kato et al., 2005 [PubMed 15994936]) .
NCBI Gene ID
54920
Swiss Prot
Q9NX74
Accession Number
Q9NX74
Host
Rabbit
Reactivity
Human
Immunogen
This DUS2L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 371-397 amino acids from the C-terminal region of human DUS2L.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
55 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
DUS2
NCBI Official Name
TRNA-dihydrouridine (20) synthase [NAD (P) +]-like
NCBI Organism
Homo sapiens
Background Reference 01
Mittelstadt, M., et al. Nucleic Acids Res. 36 (3) :998-1008 (2008)
Background Reference 02
Sugiyama, N., et al. Mol. Cell Proteomics 6 (6) :1103-1109 (2007)
Background Reference 03
Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)
Background Reference 04
Kato, T., et al. Cancer Res. 65 (13) :5638-5646 (2005)
Other Product Names
TRNA-dihydrouridine (20) synthase [NAD (P) +]-like, 131-, Dihydrouridine synthase 2, Up-regulated in lung cancer protein 8, URLC8, tRNA-dihydrouridine synthase 2-like, hDUS2, DUS2, DUS2L
Tested Applications
WB
Protein ID
73620832
Physical Properties
Liquid

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