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SS18L1 Antibody

CAT: 0223-59-703Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-59-703Size:400 µL
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Background
Synovial sarcomas occur most frequently in the extremities around large joints. More than 90% of cases have a recurrent and specific chromosomal translocation, t (X;18) (p11.2; q11.2), in which the 5-prime end of the SS18 gene (MIM 600192) is fused in-frame to the 3-prime end of the SSX1 (MIM 312820), SSX2 (MIM 300192), or SSX4 (MIM 300326) gene. The SS18L1 gene is homologous to SS18.
NCBI Gene ID
26039
Swiss Prot
O75177
Accession Number
O75177
Host
Rabbit
Reactivity
Human
Immunogen
This SS18L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 272-300 amino acids from the Central region of human SS18L1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
43 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
SS18L1
NCBI Official Name
Calcium-responsive transactivator
NCBI Organism
Homo sapiens
Background Reference 01
Yoshida, T., et al. Int. J. Mol. Med. 25 (4) :649-656 (2010)
Background Reference 02
Oguri, M., et al. Am. J. Hypertens. 23 (1) :70-77 (2010)
Background Reference 03
Yoshida, T., et al. Int. J. Mol. Med. 24 (4) :539-547 (2009)
Background Reference 04
De Bruijn, D.R., et al. Cytogenet. Genome Res. 112 (3-4), 222-226 (2006) :
Other Product Names
Calcium-responsive transactivator, SS18-like protein 1, SYT homolog 1, SS18L1, CREST, KIAA0693
Tested Applications
WB
Physical Properties
Liquid