MDH2 Antibody

• Background:

  Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. The protein encoded by this gene is localized to the mitochondria and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. [provided by RefSeq].

• NCBI Gene ID:

  4191

• Swiss Prot:

  P40926

• Accession Number:

  P40926

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This MDH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 297-326 amino acids from the C-terminal region of human MDH2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Monkey

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  36 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  MDH2

• NCBI Official Name:

  Malate dehydrogenase, mitochondrial

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Rose, J. Phd, et al. Mol. Med. (2010) In press :

• Background Reference 02:

  Rzem, R., et al. J. Inherit. Metab. Dis. 30 (5) :681-689 (2007)

• Background Reference 03:

  Luo, C., et al. J. Biochem. Biophys. Methods 68 (2) :101-111 (2006)

• Background Reference 04:

  Kullberg, M., et al. Mol. Biol. Evol. 23 (8) :1493-1503 (2006)

• Other Product Names:

  Malate dehydrogenase, mitochondrial, MDH2

• Tested Applications:

  WB

• Protein ID:

  215274114

• Physical Properties:

  Liquid