GNMT Antibody

• Background :

  The protein encoded by this gene is an enzyme that catalyzes the conversion of S-adenosyl-L-methionine (along with glycine) to S-adenosyl-L-homocysteine and sarcosine. The encoded protein is found in the cytoplasm and acts as a homotetramer. Defects in this gene are a cause of GNMT deficiency (hypermethioninemia) .

• NCBI Gene ID :

  27232

• Swiss Prot :

  Q14749

• Accession Number :

  Q14749

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This GNMT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 78-106 amino acids from the Central region of human GNMT.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Obesity, Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Homology :

  Predicted species reactivity based on immunogen sequence: Pig, Rabbit

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  33 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  GNMT

• NCBI Official Name :

  Glycine N-methyltransferase

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Jugessur, A., et al. PLoS ONE (7), E11493 (2010) :

• Background Reference 02 :

  Lee, C.M., et al. Gene 443 (1-2), 151-157 (2009) :

• Background Reference 03 :

  Boyles, A.L., et al. Genet. Epidemiol. 33 (3) :247-255 (2009)

• Background Reference 04 :

  Yen, C.H., et al. Toxicol. Appl. Pharmacol. 235 (3) :296-304 (2009)

• Other Product Names :

  Glycine N-methyltransferase, GNMT

• Tested Applications :

  WB

• Protein ID :

  12644416

• Physical Properties :

  Liquid