GPT2 Antibody

• Background:

  GPT (MIM 138200) and GPT2 (EC 2.6.1.2), also known as alanine transaminases, are pyridoxal enzymes that catalyze the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate. By mediating the conversion of these 4 major intermediate metabolites, these transaminases have roles in gluconeogenesis and in amino acid metabolism.

• NCBI Gene ID:

  84706

• Swiss Prot:

  Q8TD30

• Accession Number:

  Q8TD30

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This GPT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-44 amino acids from the N-terminal region of human GPT2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  58 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  GPT2

• NCBI Official Name:

  Alanine aminotransferase 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Glinghammar, B., et al. Int. J. Mol. Med. 23 (5) :621-631 (2009)

• Background Reference 02:

  Fraser, A., et al. Hepatology 46 (1) :158-165 (2007)

• Background Reference 03:

  Ding, Y., et al. World J. Gastroenterol. 12 (43) :7038-7041 (2006)

• Background Reference 04:

  Martin, J., et al. Nature 432 (7020) :988-994 (2004)

• Other Product Names:

  Alanine aminotransferase 2, ALT2, Glutamate pyruvate transaminase 2, GPT 2, Glutamic--alanine transaminase 2, Glutamic--pyruvic transaminase 2, GPT2, AAT2, ALT2

• Tested Applications:

  WB

• Protein ID:

  74730602

• Physical Properties:

  Liquid