GORASP1 Antibody

• Background:

  The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is a membrane protein involved in establishing the stacked structure of the Golgi apparatus. It is a caspase-3 substrate, and cleavage of this encoded protein contributes to Golgi fragmentation in apoptosis. This encoded protein can form a complex with the Golgi matrix protein GOLGA2, and this complex binds to the vesicle docking protein p115. Several alternatively spliced transcript variants of this gene have been identified, but their full-length natures have not been determined.

• NCBI Gene ID:

  64689

• Swiss Prot:

  Q9BQQ3

• Accession Number:

  Q9BQQ3

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This GORASP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 91-119 amino acids from the Central region of human GORASP1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  46 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  GORASP1

• NCBI Official Name:

  Golgi reassembly-stacking protein 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

• Background Reference 02:

  Tang, D., et al. Traffic 11 (6) :827-842 (2010)

• Background Reference 03:

  Xiang, Y., et al. J. Cell Biol. 188 (2) :237-251 (2010)

• Background Reference 04:

  D'Angelo, G., et al. J. Biol. Chem. 284 (50) :34849-34860 (2009)

• Other Product Names:

  Golgi reassembly-stacking protein 1, Golgi peripheral membrane protein p65, Golgi phosphoprotein 5, GOLPH5, Golgi reassembly-stacking protein of 65 kDa, GRASP65, GORASP1, GOLPH5, GRASP65

• Tested Applications:

  WB

• Protein ID:

  51316077

• Physical Properties:

  Liquid