Products for Research Use Only
RegisterLogin

PDCD10 Antibody

CAT: 0223-59-576Size: 400 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-59-576Size:400 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq].
NCBI Gene ID
11235
Swiss Prot
Q9BUL8
Accession Number
Q9BUL8
Host
Rabbit
Reactivity
Human
Immunogen
This PDCD10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 96-124 amino acids from the Central region of human PDCD10.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Cell Cycle, Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Zebrafish, Chicken, Mouse, Rat, Xenopus
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
25 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PDCD10
NCBI Official Name
Programmed cell death protein 10
NCBI Organism
Homo sapiens
Background Reference 01
Lauenborg, B., et al. APMIS 118 (10) :719-728 (2010)
Background Reference 02
Shimada, M., et al. Hum. Genet. 128 (4) :433-441 (2010)
Background Reference 03
Ding, J., et al. Biochem. Biophys. Res. Commun. 399 (4) :587-592 (2010)
Background Reference 04
Zheng, X., et al. J. Clin. Invest. 120 (8) :2795-2804 (2010)
Other Product Names
Programmed cell death protein 10, Cerebral cavernous malformations 3 protein, TF-1 cell apoptosis-related protein 15, PDCD10, CCM3, TFAR15
Tested Applications
WB
Protein ID
74733232
Physical Properties
Liquid

Related Products

CatalogName
92-082PDCD10 Recombinant Protein
60-550PDCD2L Antibody
30-652PDCD2L Antibody
22-911PDCD2L Antibody
34-063Recombinant PDCD1 / PD-1 Antibody [PDCD1/1410R]
33-741PDCD1 / PD-1 Antibody
31-081PDCD4 Antibody
43-063PDCD4 Antibody
43-062PDCD4 Antibody
22-844PDCD5 Antibody

Alternative Products

CatalogName
70R-35072PDCD10 antibody

Popular Products