Recombinant PDCD1 / PD-1 Antibody [PDCD1/1410R]

• Background:

  PDCD1 (Programmed cell death-1 protein), also called PD1 and CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD1 is expressed by few B-cells, so may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma.

• NCBI Gene ID:

  5133

• Swiss Prot:

  Q15116

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  A partial length human protein was used as the immunogen for the recombinant PD1 antibody.

• Clonality:

  Recombinant Monoclonal

• Clone:

  PDCD1/1410R

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology, Cancer, Cell Cycle

• Purification:

  Protein A affinity chromatography

• Concentration:

  0.2 mg/mL

• Buffer:

  PBS with 0.1 mg/ml BSA and 0.05% sodium azide

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.

• Fragment:

  IgG, k

• Applications Notes:

  1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

• Symbol:

  PDCD1

• NCBI Official Name:

  Programmed cell death 1

• NCBI Organism:

  Mus musculus

• Other Product Names:

  PD-1 Antibody: PD1, PD-1, CD279, SLEB2, hPD-1, hPD-l, hSLE1, PD1, Programmed cell death protein 1, Protein PD-1, PDCD1, PDCD-1

• Tested Applications:

  IHC-P, IF, Flow

• Physical Properties:

  Liquid