TFAP2D Antibody

• Background:

  Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC (By similarity) .

• NCBI Gene ID:

  83741

• Swiss Prot:

  Q7Z6R9

• Accession Number:

  Q7Z6R9

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This TFAP2D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 308-336 amino acids from the C-terminal region of human TFAP2D.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  50 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  TFAP2D

• NCBI Official Name:

  Transcription factor AP-2-delta

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Kim, J.M., et al. DNA Res. 13 (6) :275-286 (2006)

• Background Reference 02:

  Wenke, A.K., et al. Biochem. Biophys. Res. Commun. 345 (1) :495-501 (2006)

• Background Reference 03:

  Cheng, C., et al. Int. J. Biochem. Cell Biol. 34 (1) :78-86 (2002)

• Other Product Names:

  HGNC:15581

• Tested Applications:

  WB, IF

• Protein ID:

  74750179

• Physical Properties:

  Liquid