MSC Antibody

• Background :

  The protein encoded by this gene is a transcriptional repressor capable of binding an E-box element either as a homodimer or as a heterodimer with E2A in vitro. The encoded protein also forms heterodimers with E2A proteins in vivo. This protein is capable of inhibiting the transactivation capability of E47, an E2A protein, in mammalian cells. This gene is a downstream target of the B-cell receptor signal transduction pathway. [provided by RefSeq].

• NCBI Gene ID :

  9242

• Swiss Prot :

  O60682

• Accession Number :

  O60682

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  This MSC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-194 amino acids from the C-terminal region of human MSC.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Other

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  22 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  MSC

• NCBI Official Name :

  Musculin

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Jugessur, A., et al. PLoS ONE (7), E11493 (2010) :

• Background Reference 02 :

  Ushmorov, A., et al. Leukemia 22 (10) :1942-1944 (2008)

• Background Reference 03 :

  Knight, J.C., et al. Nat. Genet. 36 (4) :394-399 (2004)

• Background Reference 04 :

  Wong, J., et al. DNA Cell Biol. 20 (8) :465-471 (2001)

• Other Product Names :

  Musculin, Activated B-cell factor 1, ABF-1, Class A basic helix-loop-helix protein 22, bHLHa22, MSC, ABF1, BHLHA22

• Tested Applications :

  WB

• Physical Properties :

  Liquid