UAP1 Antibody

• Background:

  UAP1 converts UDP and GlcNAc-1-P into UDP-GlcNAc, and UDP and GalNAc-1-P into UDP-GalNAc. Isoform AGX1 has 2 to 3 times higher activity towards GalNAc-1-P, while isoform AGX2 has 8 times more activity towards GlcNAc-1-P.

• NCBI Gene ID:

  6675

• Swiss Prot:

  Q16222

• Accession Number:

  Q16222

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This UAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 390-418 amino acids from the C-terminal region of human UAP1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  59 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  UAP1

• NCBI Official Name:

  UDP-N-acetylhexosamine pyrophosphorylase

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Ehret, G.B., et al. Eur. J. Hum. Genet. 17 (12) :1650-1657 (2009)

• Background Reference 02:

  Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345 (3) :1022-1032 (2006)

• Background Reference 03:

  Peneff, C., et al. EMBO J. 20 (22) :6191-6202 (2001)

• Background Reference 04:

  Wang-Gillam, A., et al. J. Biol. Chem. 273 (42) :27055-27057 (1998)

• Other Product Names:

  UDP-N-acetylhexosamine pyrophosphorylase, Antigen X, AGX, Sperm-associated antigen 2, UDP-N-acetylgalactosamine pyrophosphorylase, AGX-1, UDP-N-acetylglucosamine pyrophosphorylase, AGX-2, UAP1, SPAG2

• Tested Applications:

  WB

• Protein ID:

  68846235

• Physical Properties:

  Liquid