GJC3 Antibody

• Background:

  This gene encodes a gap junction protein. The encoded protein, also known as a connexin, plays a role in formation of gap junctions, which provide direct connections between neighboring cells. Mutations in this gene have been reported to be associated with nonsyndromic hearing loss.

• NCBI Gene ID:

  349149

• Swiss Prot:

  Q8NFK1

• Accession Number:

  Q8NFK1

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This GJC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 252-278 amino acids from the C-terminal region of human GJC3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  31 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  GJC3

• NCBI Official Name:

  Gap junction gamma-3 protein

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Yang, J.J., et al. Hum. Genet. 128 (3) :303-313 (2010)

• Background Reference 02:

  Ramchander, P.V., et al. Genet Test Mol Biomarkers 14 (4) :539-541 (2010)

• Background Reference 03:

  Hong, H.M., et al. Hum. Genet. 127 (2) :191-199 (2010)

• Background Reference 04:

  Wang, W.H., et al. Audiol. Neurootol. 15 (2) :81-87 (2010)

• Other Product Names:

  Gap junction gamma-3 protein, Connexin-302, Cx302, Connexin-313, Cx313, Gap junction epsilon-1 protein, GJC3, GJE1

• Tested Applications:

  WB

• Protein ID:

  32171365

• Physical Properties:

  Liquid