SCNN1B Antibody

• Background:

  When expressed in the bladder epithelium, the protein encoded by the SCNN1B gene might be implicated in the mechanosensory transduction in the bladder afferent pathways, thereby inducing detrusor instability by outlet obstruction. Common variants of this gene confer susceptibility to human essential hypertension.

• NCBI Gene ID:

  6338

• Swiss Prot:

  P51168

• Accession Number:

  NP_000327

• Host:

  Rabbit

• Reactivity:

  Human, Dog

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SCNN1B.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Membrane, Signal Transduction

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. 1205 - Jurkat Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SCNN1B antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  70 kDa

• Applications Notes:

  SCNN1B antibody can be used for detection of SCNN1B by ELISA at 1:312500. SCNN1B antibody can be used for detection of SCNN1B by western blot at 0.125 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  SCNN1B

• NCBI Official Name:

  Sodium channel, non-voltage-gated 1, beta subunit

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Snyder, P.M., et al., (2004) J. Biol. Chem. 279 (44), 45753-45758.

• Other Product Names:

  SCNN1B, BESC1, ENaCb, SCNEB, ENaCbeta

• Tested Applications:

  ELISA, WB

• Protein ID:

  124301196

• Physical Properties:

  Liquid