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SCNN1B Antibody

CAT: 0223-28-219Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-28-219Size:100 µL
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Background
When expressed in the bladder epithelium, the protein encoded by the SCNN1B gene might be implicated in the mechanosensory transduction in the bladder afferent pathways, thereby inducing detrusor instability by outlet obstruction. Common variants of this gene confer susceptibility to human essential hypertension.
NCBI Gene ID
6338
Swiss Prot
P51168
Accession Number
NP_000327
Host
Rabbit
Reactivity
Human, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SCNN1B.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane, Signal Transduction
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SCNN1B antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
70 kDa
Applications Notes
SCNN1B antibody can be used for detection of SCNN1B by ELISA at 1:312500. SCNN1B antibody can be used for detection of SCNN1B by western blot at 0.125 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
SCNN1B
NCBI Official Name
Sodium channel, non-voltage-gated 1, beta subunit
NCBI Organism
Homo sapiens
Background Reference 01
Snyder, P.M., et al., (2004) J. Biol. Chem. 279 (44), 45753-45758.
Other Product Names
SCNN1B, BESC1, ENaCb, SCNEB, ENaCbeta
Tested Applications
ELISA, WB
Protein ID
124301196
Physical Properties
Liquid

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