ZFP36L2 Antibody

• Background:

  This gene is a member of the TIS11 family of early response genes. Family members are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors.

• NCBI Gene ID:

  678

• Swiss Prot:

  P47974

• Accession Number:

  P47974

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This ZFP36L2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-193 amino acids from the Central region of human ZFP36L2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Rat, Xenopus

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  51 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  ZFP36L2

• NCBI Official Name:

  Zinc finger protein 36, C3H1 type-like 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Morgan, B.R., et al. Protein Sci. 19 (6) :1222-1234 (2010)

• Background Reference 02:

  Jackson, R.S. II, et al. Cell Cycle 5 (24) :2889-2893 (2006)

• Background Reference 03:

  Hudson, B.P., et al. Nat. Struct. Mol. Biol. 11 (3) :257-264 (2004)

• Background Reference 04:

  Blackshear, P.J., et al. Prog. Nucleic Acid Res. Mol. Biol. 75, 43-68 (2003) :

• Other Product Names:

  Zinc finger protein 36, C3H1 type-like 2, ZFP36-like 2, Butyrate response factor 2, EGF-response factor 2, ERF-2, Protein TIS11D, ZFP36L2, BRF2, ERF2, RNF162C, TIS11D

• Tested Applications:

  WB

• Protein ID:

  146291085

• Physical Properties:

  Liquid