DACH1 Antibody

• Background :

  This gene encodes a chromatin-associated protein that associates with other DNA-binding transcription factors to regulate gene expression and cell fate determination during development. The protein contains a Ski domain that is highly conserved from Drosophila to human. Expression of this gene is lost in some forms of metastatic cancer, and is correlated with poor prognosis. Multiple transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID :

  1602

• Swiss Prot :

  Q9UI36

• Accession Number :

  Q9UI36

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  This DACH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 270-297 amino acids from the Central region of human DACH1.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cancer

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  79 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  DACH1

• NCBI Official Name :

  Dachshund homolog 1

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Bailey, S.D., et al. Diabetes Care (2010) In press :

• Background Reference 02 :

  Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

• Background Reference 03 :

  Kottgen, A., et al. Nat. Genet. 42 (5) :376-384 (2010)

• Background Reference 04 :

  Zhou, J., et al. Proc. Natl. Acad. Sci. U.S.A. 107 (15) :6864-6869 (2010)

• Other Product Names :

  Dachshund homolog 1, Dach1, DACH1, DACH

• Tested Applications :

  WB

• Protein ID :

  519668677

• Physical Properties :

  Liquid