SNTB1 Antibody

• Background:

  Dystrophin is a large, rod-like cytoskeletal protein found at the inner surface of muscle fibers. Dystrophin is missing in Duchenne Muscular Dystrophy patients and is present in reduced amounts in Becker Muscular Dystrophy patients. The protein encoded by this gene is a peripheral membrane protein found associated with dystrophin and dystrophin-related proteins. This gene is a member of the syntrophin gene family, which contains at least two other structurally-related genes.

• NCBI Gene ID:

  6641

• Swiss Prot:

  Q13884

• Accession Number:

  Q13884

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This SNTB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 243-271 amino acids from the Central region of human SNTB1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  58 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  SNTB1

• NCBI Official Name:

  Beta-1-syntrophin

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Rothenberg, M.E., et al. Nat. Genet. 42 (4) :289-291 (2010)

• Background Reference 02:

  Sugiyama, N., et al. Mol. Cell Proteomics 6 (6) :1103-1109 (2007)

• Background Reference 03:

  Chen, Z., et al. J. Biol. Chem. 281 (18) :12414-12420 (2006)

• Background Reference 04:

  Ejtehadi, H.D., et al. Ann. Rheum. Dis. 65 (5) :612-616 (2006)

• Other Product Names:

  Beta-1-syntrophin, 59 kDa dystrophin-associated protein A1 basic component 1, DAPA1B, BSYN2, Syntrophin-2, Tax interaction protein 43, TIP-43, SNTB1, SNT2B1

• Tested Applications:

  WB

• Protein ID:

  23822159

• Physical Properties:

  Liquid