SCO2 Antibody

CAT: 0223-59-349Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-59-349Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Cytochrome c oxidase (COX) catalyzes the transfer of electrons from cytochrome c to molecular oxygen, which helps to maintain the proton gradient across the inner mitochondrial membrane that is necessary for aerobic ATP production. Human COX is a multimeric protein complex that requires several assembly factors; this gene encodes one of the COX asembly factors. The encoded protein is a metallochaperone that is involved in the biogenesis of cytochrome c oxidase subunit II. Mutations in this gene are associated with fatal infantile encephalocardiomyopathy.
NCBI Gene ID
9997
Swiss Prot
O43819
Accession Number
O43819
Host
Rabbit
Reactivity
Human
Immunogen
This SCO2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 196-224 amino acids from the C-terminal region of human SCO2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
30 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
SCO2
NCBI Official Name
Protein SCO2 homolog, mitochondrial
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 02
Foltopoulou, P.F., et al. Biochim. Biophys. Acta 1802 (6) :497-508 (2010)
Background Reference 03
Pronicki, M., et al. Eur. J. Paediatr. Neurol. 14 (3) :253-260 (2010)
Background Reference 04
Kamatani, Y., et al. Nat. Genet. 42 (3) :210-215 (2010)
Other Product Names
Protein SCO2 homolog, mitochondrial, SCO2
Tested Applications
WB
Physical Properties
Liquid

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