Products for Research Use Only
RegisterLogin

PDZD3 Antibody

CAT: 0223-59-347Size: 400 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-59-347Size:400 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Guanylyl cyclase C (GCC, or GUCY2C; MIM 601330) produces cGMP following the binding of either endogenous ligands or heat-stable enterotoxins secreted by E. coli and other enteric bacteria. Activation of GCC initiates a signaling cascade that leads to phosphorylation of the cystic fibrosis transmembrane conductance regulator (CFTR; MIM 602421), followed by a net efflux of ions and water into the intestinal lumen. IKEPP is a regulatory protein that associates with GCC and regulates the amount of cGMP produced following receptor stimulation (Scott et al., 2002 [PubMed 11950846]) .
NCBI Gene ID
79849
Swiss Prot
Q86UT5
Accession Number
Q86UT5
Host
Rabbit
Reactivity
Human
Immunogen
This PDZD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 258-285 amino acids from the Central region of human PDZD3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
61 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PDZD3
NCBI Official Name
Na (+) /H (+) exchange regulatory cofactor NHE-RF4
NCBI Organism
Homo sapiens
Background Reference 01
Zachos, N.C., et al. Cell. Physiol. Biochem. 22 (5-6), 693-704 (2008) :
Background Reference 02
Kato, Y., et al. Mol. Pharmacol. 67 (3) :734-743 (2005)
Background Reference 03
Hegedus, T., et al. Biochem. Biophys. Res. Commun. 302 (3) :454-461 (2003)
Background Reference 04
Scott, R.O., et al. J. Biol. Chem. 277 (25) :22934-22941 (2002)
Other Product Names
Na (+) /H (+) exchange regulatory cofactor NHE-RF4, NHERF-4, Intestinal and kidney-enriched PDZ protein, Natrium-phosphate cotransporter IIa C-terminal-associated protein 2, Na/Pi cotransporter C-terminal-associated protein 2, NaPi-Cap2, PDZ domain-containing protein 2, PDZ domain-containing protein 3, Sodium-hydrogen exchanger regulatory factor 4, PDZD3, IKEPP, NHERF4, PDZK2
Tested Applications
WB
Protein ID
308153467
Physical Properties
Liquid

Related Products

CatalogName
57-152PDZD4 Antibody
64-160WAS Antibody
60-596WAS Antibody
13-349WAS Antibody
62-828Neprilysin Antibody
61-580CAPZB Antibody
55-580HCG_2024410 Antibody
30-580ACPT Antibody
19-580FABP3 Antibody
15-580POMGNT2 Antibody

Alternative Products

CatalogName
GTR18150273PDZD3 Antibody
MBS9132132-01PDZD3 Polyclonal Antibody
PAab06296Anti-PDZD3 antibody
E45M07083G-1PDZD3 Antibody (Center)
CSB-CL774807HUPDZD3

Popular Products