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BTN3A3 Antibody

CAT: 0223-59-343Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-59-343Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC) -associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene (MIM 601610) and the BTN2 (e.g., BTN2A1; MIM 613590) and BTN3 (e.g., BNT3A3) genes, which have undergone tandem duplication, resulting in 3 copies of each (summary by Smith et al., 2010 [PubMed 20208008]) .[supplied by OMIM].
NCBI Gene ID
10384
Swiss Prot
O00478
Accession Number
O00478
Host
Rabbit
Reactivity
Human
Immunogen
This BTN3A3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 67-96 amino acids from the N-terminal region of human BTN3A3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
65 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
BTN3A3
NCBI Official Name
Butyrophilin subfamily 3 member A3
NCBI Organism
Homo sapiens
Background Reference 01
Smith, I.A., et al. J. Immunol. 184 (7) :3514-3525 (2010)
Background Reference 02
Zhang, Z., et al. Protein Sci. 13 (10) :2819-2824 (2004)
Background Reference 03
Rhodes, D.A., et al. Genomics 71 (3) :351-362 (2001)
Background Reference 04
Henry, J., et al. Immunol. Today 20 (6) :285-288 (1999)
Other Product Names
Butyrophilin subfamily 3 member A3, BTN3A3, BTF3
Tested Applications
WB
Physical Properties
Liquid

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